Friday, June 17, 2016

What is HEBERPROT-P - diabetic foot ulcer heberprot-p novel cure in Cuba

Diabetes can be managed effectively and controlled once it has been accurately diagnosed. The goal of diabetes management is to prevent short-and long-term complications of diabetes from developing.

Diabetic foot ulcer is a principal diabetic complication. Unfortunately, 84% of lower-limb amputations are an effect of so-called diabetic foot, chronic foot ulcers suffered by 15 to 20 percent of diabetes patients at some point in their lives. Ten to 25 percent of these patients will end up having some kind of amputation. It could be said that every 30 seconds, a diabetes patient of either sex is being amputated in a health center somewhere in the world. About 50 percent of these patients undergo a second amputation on their other lower limb. After a major amputation, fewer than 50 percent of amputees survive for more than five years.

HEBERPROT-P is a drug for stimulating and sustaining scar formation for chronic ulcers of all types on the lower extremities of diabetic patients

It's a new injectable medicine developed by eminent Cuban scientists at the national Genetic Engineering and Biotechnology Center (CIGB), together with highly qualified professionals of the National Institute of Angiology and Vascular Surgery. Heberprot-P is an innovative Cuban product containing recombinant human epidermal growth factor for peri- and intra-lesional infiltration. Its therapeutic properties, method of application and niche indications are unique internationally. Evidence reveals it accelerates healing of deep and complex ulcers, both ischemic and neuropathic, and reduces diabetes-related amputations. Without any kind of disfiguring surgery, its application through intralesional injection into the diabetic foot ulcers accelerates their scar formation, even for deep and complex ones, also reducing the number and spread of extirpation and debridement of dead or necrotic tissue. In preventing recidivism, there is an evident reduction of time for scar formation, and other complications are avoided, such as gangrene and infections. Clinical trials of Heberprot-P in patients with diabetic foot ulcers have shown that repeated local infiltration of this product can enhance curing of chronic wounds safely and efficaciously. As a result, Heberprot-P was registered in Cuba in 2006, and in 2007 was included in the National Basic Medications List and approved for marketing. It has been registered in 15 other countries, enabling treatment of more than 100,000 patients. (

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